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You are here: Home / Grant / PEPFAR: Combination Prevention Solutions to reach Epidemic Control in South Africa

PEPFAR: Combination Prevention Solutions to reach Epidemic Control in South Africa

Deadline: 20 February 2025

The United States Department of Health and Human Services is seeking grant proposals to provide targeted combination prevention solutions and approaches to vulnerable, high-risk priority populations, including adolescents and young people, aged between 10-24, in workplaces, schools, and communities.

Aims

  • The NOFO aims to create demand for and support the use of the following prevention and response interventions through direct service delivery, referrals, and technical assistance:
    • Evidence-based biomedical interventions such as:
      • HIV testing services.
      • Antiretroviral therapy.
      • Pre-exposure prophylaxis (PrEP).
      • Post-exposure prophylaxis (PEP).
      • Condom promotion and distribution.
      • Sexually transmitted infection (STI) screening and treatment.
      • Sexual and reproductive health.
      • Mental health and substance abuse screening.
      • Psychosocial support.
      • Minimum package of post-violence care.
    • Behavioral interventions such as:
      • School and community-based HIV and violence prevention, including health education for all adolescents and youth as well as community leaders, parents, and caregivers.
      • HIV risk reduction.
    • Structural HIV, TB, and violence interventions such as social mobilization.
    • Youth empowerment such as:
      • Economic strengthening.
      • Gender norm changes.
      • Gender-based violence (GBV) prevention.
      • Family strengthening programs.

Funding Information

  • Expected total NOFO funding for Year 1: $25,000,000
  • Expected number of awards: 2. The number of awards is subject to available funds and program priorities
  • Duration: They plan to award projects for five 12-month budget periods for a five-year period of performance.

Eligible Activities

  • Implement and scale-up HIV combination prevention solutions in priority districts for vulnerable, high-risk priority populations (adolescents, young people, male sex partners, and their families) to increase their knowledge, risk perception, and service uptake.
  • Provide high-quality, confidential community HIV testing and counseling services to adolescents, young people, and male sex partners to refer and link them to comprehensive prevention and treatment services.
  • Collaborate with key stakeholders to design, strengthen, and implement quality youth-responsive HIV services for adolescents and young people, following the national guidelines to improve access to prevention and treatment services.

Eligibility Criteria

  • This is a fully competitive NOFO, and eligibility is unrestricted. Any and all types of organizations are eligible and encouraged to apply, including but not limited to those listed below:
    • State governments
    • County governments
    • City or township governments
    • Special district governments
    • Independent school districts
    • Public and state-controlled institutions of higher education
    • Native American tribal governments (federally recognized)
    • Public housing authorities and Indian housing authorities
    • Native American tribal organizations, other than federally recognized tribal governments
    • Nonprofits having a 501(c)(3) status, other than institutions of higher education
    • Nonprofits without 501(c)(3) status, other than institutions of higher education
    • Private institutions of higher education
    • For-profit organizations other than small businesses
    • Small businesses
    • Foreign or non-U.S. based entities.

For more information, visit Grants.gov.

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