Deadline: 25 March 2024
The Alex’s Lemonade Stand Foundation (ALSF) has launched the Reach Grant to remove barriers by providing support for important pre-clinical hypothesis-driven research projects that are necessary to move a study from the preclinical arena into a clinical trial.
Thus, the goal of this award is to support translational studies that will result in a phase 1 and/or 2 clinical trial, two to three years from the project end date. Examples of appropriate research projects include but aren’t limited to, completing IND-enabling studies, providing requisite pre-clinical data for clinical trial development, or perhaps through the validation of biomarkers that will enable selection of the correct patients for entry into new clinical trials.
Scope of Proposal
- Proposals must fall within the scope of Alex’s Lemonade Stand Foundation’s mission, focused on childhood cancers. Proposals with a sole/primary focus on patients >19 years of age will not be considered.
- Proposals will be evaluated based on their late-translational potential. Thus, screening projects, discovery projects, and early translational projects are not appropriate for the Reach Grant.
- The proposal must be hypothesis driven and demonstrate feasibility. Preliminary data are required.
- Proposals should be milestone driven; explicit timeline and time-based deliverables for the proposed studies must be presented.
- Proposal must include a plan to bring project to a clinical trial. Projects with a clear plan will be prioritized.
Budget
- The requested budget should be in proportion to the scope of the proposed project and should be for direct costs of $250,000 USD or below over 2 years. A maximum of $125,000 in total direct costs may be requested per year.
Eligibility Criteria
- Applicant institutions must be based in the United States or Canada. Applicants need not be United States citizens. Funds must be granted to nonprofit institutions or organizations.
- Applicants must have an MD, PhD, or MD/PhD or equivalent and be appointed as faculty (or equivalent) at an academic institution.
- Applicants must have a demonstrated track record of pediatric cancer researchwith experience in translational research.
- Multiple investigator applications that bring together pairs or teams of researchers with complementary expertise are encouraged.
For more information, visit Alex’s Lemonade Stand Foundation (ALSF).
